Posted by ed_uk on April 2, 2006, at 15:14:50
In reply to Re: Is Valium more potent than Xanax? » ed_uk, posted by zeugma on April 2, 2006, at 14:29:01
Hi Z
Clonazepam has been looked at to 'augment' antidepressants. I think the research was Japanese.
>reports here, in which I have seen far more frequent attributions of depression to clonazepam than to any of the other benzos
That's true. Most babblers compare it to Xanax though. In many cases they haven't taken any other benzodiazepines.
>Patients with unipolar depression had significantly (P=0.026) less depressive episodes after initiation of treatment with clonazepam. Patients with bipolar disorder did not benefit from this therapy. Neither manic/hypomanic phases nor depressive episodes were reduced in this group of patients. Interestingly, clonazepam also reduced affective phases in our four schizoaffective patients on a trend level. Our results indicate that patients with unipolar depression may benefit from a maintenance treatment with clonazepam.
That's interesting. I would not consider clonazepam to be a 'mood stabiliser'. There seems to be a trend to refer to all antiepileptics as mood stabilisers, even in the absense of evidence.....Topamax being the most obvious example today..........gabapentin a few years ago.........probably Keppra next.
Kind regards
Ed
poster:ed_uk
thread:627071
URL: http://www.dr-bob.org/babble/20060329/msgs/627882.html