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Re: MAOI / Trz Checking Drug Interactions Online » JaclinHyde

Posted by yxibow on April 1, 2006, at 12:26:34

In reply to MAOI interaction with Trazodone, posted by JaclinHyde on April 1, 2006, at 1:47:45

> Sigh...guess what I found?
>
> "Drug Interactions:
> Trazodone may enhance the response to alcohol and the effects of barbiturates and other CNS depressants and patients should be cautioned accordingly.
>
> Increased serum digoxin and phenytoin levels have been reported to occur in patients receiving trazodone concurrently with either of those 2 drugs. Little is known about the interaction between trazodone and general anesthetics; therefore, prior to elective surgery, trazodone should be discontinued for as long as clinically feasible.
>
> ****Because it is not known whether an interaction will occur between trazodone and MAO inhibitors, administration of trazodone should be initiated very cautiously with gradual increase in dosage as required, if an MAO inhibitor is given concomitantly or has been discontinued shortly before medication with trazodone is instituted.****
>
> (And Tyler.....)
>
> *****Trazodone may cause hypotension including orthostatic hypotension and syncope; caution is required if it is given to patients receiving antihypertensive drugs and an adjustment in the dose of the antihypertensive medication may be required.*****
>
> Ambien CR has just become my new best friend :-)


:) And a much better sleep aid, or Lunesta, up to 3 mg/dy. I believe in REM promoting, pure sleep aids.

You can also check, which mentions this interaction in bold red, at

http://www.drugs.com/drug_interactions.html

You just click yes on the legalese and then go enter all your medications one by one and see if there are especially any red marks. Its not perfect but its one of the better ones out there

 

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URL: http://www.dr-bob.org/babble/20060329/msgs/627476.html