Posted by Joe Schmoe on November 17, 2005, at 12:31:57
Can anyone clear up for me what the interaction is with GABA / dopamine, and how Nardil affects it vs. Selegiline (I am interested in MAOI drugs now because of Emsam).
I have read low dopamine levels are implicated in social phobia, as are low GABA levels and serotonin as well, and that is why Nardil works - it raises all three. Also I know benzos like Klonopin are used to treat low GABA levels and are used for social phobia.
But I have also read that GABA inhibits dopamine activity. I don't understand the theory behind raising both of them, or why raising just GABA (via Klonopin) would help if doing so lowers dopamine activity.
I am also curious if Selegiline / Emsam will affect GABA at all, or whether it will require Klonopin as well in order to combat social phobia. Nardil seems to work by itself. Does Selegiline require a benzo supplement to effectively treat social phobia? If so, what advantage would Selegiline and a benzo have over an SSRI and a benzo?
Thanks.
poster:Joe Schmoe
thread:579637
URL: http://www.dr-bob.org/babble/20051112/msgs/579637.html