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Re: Amitriptyline is ok » ed_uk

Posted by darkhorse on August 14, 2005, at 12:05:42

In reply to Re: Amitriptyline is ok » KaraS, posted by ed_uk on August 14, 2005, at 9:20:27

Hi ED :

> I've always believed that amitriptyline was probably more effective. It's a much more potent serotonin and NE reuptake inhibitor than doxepin. It's a better established AD. It's probably more likely to cause tachycardia though........ but not much as desipramine.

Me too. In my opinion Doxepin is a powerful anti-histamine medican, with very mild 5ht/ne uptake as a bonus!
However I agree that Amit. is a potent NE/5ht,5ht2 antagonist,and anti- histaminic as a bonus!
Yes, desipramine gave me the 2nd worst tachycardia ever (after the pro-aggression/depressive Sibutramine).


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