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Re: pellets in capsules » Larry Hoover

Posted by Cairo on May 30, 2005, at 8:05:09

In reply to Re: pellets in capsules, posted by Larry Hoover on May 29, 2005, at 7:54:01

What about Effexor XR? I tried counting out pellets with that and I remember having different effects: one time not much, then another time feeling incredibly spacey (but my muscles completely relaxed for the first and only time since onset of Fibromyalgia). Is Effexor XR one of those that has different coatings on different pellets? That would explain my inconsistent results. Thanks.

Cairo

> Some capsules have mixtures of different coatings on different pellets, all in one capsule. One coating type instantly dissolves, giving you quick activity. Another coating is enteric, but rather thin. That gives some pellets quick release, but only when the pellets have moved out of the stomach (1-3 hours later). So, kind of a time-release mechanism. Still other pellets might have a really thick enteric coating, and they somewhat gradually get released from the intestine, further extending the maximum time of first release of part of the dose.
>
> This can allow you to take a med, for example, once every 12 hours instead of once every 4. The mix of coatings delays the release of some of medication. This also reduced the height of the peak of blood concentration, and broadens it. You get a more stable, long-term peak.
>
> General concepts.
>
> Lar
>
>


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