Posted by Optimist on February 24, 2005, at 23:37:32
In reply to Re: Parnate » Optimist, posted by ed_uk on February 24, 2005, at 11:58:26
> Hi Brian,
>
> How are your side effects? Are you still taking 60mg?
>
> >I'm sure you will find a sympathetic doctor soon if you keep plugging away.
>
> Thanks :-) I don't know how to find one though. I can't ask my new pdoc to refer me to another pdoc because he'd just say no, anyway he'd be offended.
>
> Ed.My side effects aren't too bad now. The agitation seems less noticable now, almost non-existant, and the sexual dysfunction is pretty minor. No delayed ejaculation, just a little problem with erectile quality but not that bad. Just not 100%, which I'm not expecting right now anyways. :)
Yeah, I'm still takign 60mg a day, 20 for breakfast, lunch, and dinner. Zero insomnia still, sleeping like a baby. I'm not going to lower it at the moment. I almost would prefer to go above 100mg as soon as possible if anything since it starts acting as a 5HT2a antagonist around that point, which means less agitation, sexual dysfunction, and more dopamine which I think I could use a little more of. I think I heard it reduces dopamine in the long run at more moderate doses 50-100mg, due to 5HT2a stimulation ,but I'm not completely certain.
I think I am getting better though. Perhaps mon and tues were just a blip. It's weird... Parnate is acting so subtle, it's so much more of a natural feeling. It's lifting the depression without the speediness, apathy, and bad side effects of other drugs. It's like it's hitting the exact deficiency that made me depressed in the first place. I'm sure that's not true but it sure feels like it anyways. Like the wonder and excitement of a child is returning.
I may ask my pdoc for a low dose lithium augmentation next week. I know I do have cycles to my depressions, with summers and winters being much worse. Lithium is supposed to help with hypoglycemia as well which MAOI's exacerbate. Hypoglycemia is something I've been battling for awhile, but is getting much better with the addition of high dose niacinamide, chromium, and licorice.
Are there any resources you can check regarding pdocs? How about teaching hospitals, universities, etc... If I was in your case I think I would just order the stuff my self. It's not the best option, but neither is the next 20 years of Effexor/SSRI's if they don't work for you either.
Brian
poster:Optimist
thread:460810
URL: http://www.dr-bob.org/babble/20050222/msgs/463012.html