Posted by ed_uk on January 2, 2005, at 22:29:02
Have a look at this, you might be very suprised........
Here's a link to the recent UK government report on SSRIs and related ADs...
http://www.mhra.gov.uk/news/2004/SSRIfinal.pdfUsing the 'bar' on the right hand side of the page scroll down to page 165. Have a look at how the efficacy of paroxetine (Paxil/Seroxat) compares to placebo. The results of various trials are presented in a table. As you can see, paroxetine is only slightly more effective than placebo. The MDD studies were especially disappointing.
If you continue to scroll down the page you'll see the data for other ADs, the results are very depressing to say the least.
The results for citalopram (Celexa/Cipramil) in the treatment of depression can be found on page 167 and are almost nauseatingly bad.
Keep scrolling..... the effectivness of sertraline (Zoloft) in the treatment of depression is really quite dire. 50mg Zoloft was only superior to placebo in one out of four MDD trials. In some cases, placebo seemed to be considerably more effective than high doses of Zoloft- probably due to the absence of nasty SSRI side effects.
Keep scrolling.........
poster:ed_uk
thread:437036
URL: http://www.dr-bob.org/babble/20041228/msgs/437036.html