Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: well there must be a way of creating new 5HT1A

Posted by linkadge on November 29, 2004, at 13:15:52

In reply to Re: well there must be a way of creating new 5HT1A » linkadge, posted by SLS on November 29, 2004, at 12:10:33

There are both postsynaptic and presynaptic receptors for both 5-ht1a, and 5-ht1b.

Activation of the post synaptic 5-ht1a/5-ht1b receptors is responsable for the antidepressant/antipanic effects.

If you activate the presynaptic (autoreceptors) then you shut off serotonin release. Ie you want to desensitize the presynaptic autoreceptors so that they don't get activated as much which results in more serotonin release to reach the post synaptic receptors.

People with depression have tons of really sensitive autoreceptors but their postsynaptic systems aren't working as well.


Linkadge



Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


[421880]

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:linkadge thread:420379
URL: http://www.dr-bob.org/babble/20041128/msgs/421880.html