Posted by KaraS on November 13, 2004, at 18:40:49
In reply to MILNACIPRAN (Ixel/Oxitriptan/Dalcipran/Toledomin), posted by Lilith on November 13, 2004, at 13:13:47
> Cymbalta's ratio of norepinepherine:serotonin is 1:10. Effexor's N:S is 1:30. Milnacipran's N:S ratio is SIGNIFICANTLY DIFFERENT AT 3:1--VIRTUALLY NO SIDE-EFFECTS. Milnacipran, an SNRI, is currently in Phase III clinical trials for treatment of Fibromyalgia and neurogenic pain in general. It was has been used VERY SUCCESSFULLY as an SNRI antidepressant [only] in many foreign countries for SEVERAL years. The U.S. patent is for the EXTENDED RELEASE formulation. WHY CAN'T WE GET THIS MEDICATION IN IT'S CURRENT 2X/DAY FORMULATION FOR DEPRESSION IN THE U.S. pending the [presumed] FDA approval and release of the XL formulation???
I didn't realize that this medication was pending approval here at all in any form. The limited research I did on milnacipran a while back didn't indicate that it was that effective for depression. What research have you found on this drug? I would be very glad to learn that my first impression is wrong.
Kara
poster:KaraS
thread:415452
URL: http://www.dr-bob.org/babble/20041113/msgs/415588.html