Re: Is Trazodone an SSRI?

Posted by SLS on October 26, 2004, at 16:07:50

In reply to Is Trazodone an SSRI?, posted by redscarlet on October 26, 2004, at 15:50:24

Trazodone (Desyrel) is a phenylpiperazine. It is a weak inhibitor of serotonin (5-HT) reuptake, but it does other things too. It is not really selective. It is also an antagonist of 5-HT2a and NE alpha-1 receptors. Its metabolite, mCPP, is an agonist of 5-HT2b and 5-HT2c receptors. Some literatures states that trazodone is devoid of anticholinergic side effects, others describe mild effects.

- Scott

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Is Trazodone an SSRI? redscarlet 10/26/04
Re: Is Trazodone an SSRI? SLS 10/26/04
Re: Is Trazodone an SSRI? » SLS King Vultan 10/26/04

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