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Re: Is DXM a dopamine or serotonin reptake inhibitor? » SLS

Posted by Shawn. T. on August 23, 2004, at 20:46:05

In reply to Re: Is DXM a dopamine or serotonin reptake inhibitor? » Shawn. T., posted by SLS on August 23, 2004, at 2:26:01

One theory is that sigma-1 receptors are intracellular amplifiers for signal transduction (Su and Hayashi 2003). DHEA is a sigma-1 agonist.
Sigma-2 receptors may serve a similar role; they are known to modulate neurotransmitter release.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12871086

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15089113

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14730086

Shawn

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