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Re: MAOI helping RLS (restless legs syndrome) ????

Posted by Questionmark on May 4, 2004, at 17:02:34

In reply to MAOI helping RLS (restless legs syndrome) ????, posted by jjman on May 2, 2004, at 19:30:25

> I Suffer from depression and rls (restless legs syndrome) and i want to know if MAOI
> (Nardil,Parnate,Manerix....) can help RLS. I Know that maoi increase dopamine in brain, as well as serotonine and noradrenaline, and
> rls is cause by a lack of dopamine. Is there anybody that take maoi for rls ???
>
>
> Please give me somes advices.
>
> Thanks

Parnate mIght be helpful (i have no idea), but i'm pretty sure Nardil and probably Marplan would make RLS worse. This is due to their significant serotonergic transmission, which, especially for Nardil, is greater than the increase in dopamine.

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