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Re: Risperidol and Prolactin

Posted by SLS on April 9, 2004, at 10:23:48

In reply to Risperidol and Prolactin, posted by mollyvish on April 9, 2004, at 9:22:04

> Hi - I've been taking Risperidol for 2 weeks at 1mg at bedtime (10pm). My doctor checked my prolactin level at 10:30am after the first 2 weeks and it was 88.9ng/ml.

I read that the normal range for premenopausal women is between 2 – 20 ng/ml. I don't happen to know how much increase one would expect from treatment with 1.0mg of Risperdal (risperidone), but Risperdal is known to be about the most potent of the antipsychotics, both typical and atypical, to produce increases in prolactin and hyperprolactinemia. From what I've read on Medline, levels of prolactin can exceed 50 ng/ml, and often beyond 100 ng/ml. However, the dosages of risperidone cited were generally higher than 1.0 mg.

http://www.keratin.com/ab/ab012.shtml#02

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12107619


- Scott

 

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