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Re: Lamictal for atypical depression

Posted by Tony P on March 17, 2004, at 3:15:40

In reply to Re: Lamictal for atypical depression, posted by DepNYer on March 15, 2004, at 16:01:19

> I have TR unipolar depression and use 400 mg of Lamictal to augment Remeron 45 mg, and imipramine 300 mg. I've found it to make a tremendous difference, and fairly tolerable as far as side effects. I also take klonopin for anxiety, and noticed that the Lamictal seemed to augment it's anti-anxiety effects, allowing me to substantially reduce the dose of K. I do think it can be a good drug in the right setting, and I would recommend it as an augmentation agent.

Agreed. Although Lamictal is currently officially only recommended for Bipolar, I am primarily depressed (possibly BP3 - hypomanic only on some ADs) and am finding it helpful. My pdoc uses it for both BP and straight depression, and also says it has anti-anxiety effects.

I am currently taking quite a lot of klonopin (4mg/day) and feeling a bit overmedicated (concentration/memory problems), so maybe I can reduce it as I ramp up on Lamictal. I did experience at least one major anxiety attack when my Lamictal went from 50 to 100 mg/day (that's how I got on the klonopin), but my impression is that the dose-increase anxiety (if you get it at all) is only temporary. I haven't really noticed it with smaller increments of Lamictal (200->250->300).

Tony P


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