Posted by rod on January 25, 2004, at 6:17:26
In reply to UPDATE ...... I donīt like this..., posted by Tepiaca on January 24, 2004, at 20:38:07
>
> Today was my second day on this combo.
> I dont like how Im feeling right now.
> I havenīt have any benefits on anxiety,instead my anxiety is getting just a little worst
> But the worst thing is that Im feeling depressed,
> I dont have motivation , I dont want to do anything ,not even to write this.
>
> mmmm , why is this happen?
>
> do you think I should stay more time on EPIVAL ?
>
> I thought this combo was gonna help me ,but I guess I was wrong
>
> can you help me do some conclucions ?
>
> NArdil increases gaba , so does Epival ,..rigth?
> thats mean I dont need to have an increase in the gaba system???
> I really dont know anything about this stuff
> help this one please
I cant help you to do some conclusions. Its just your 2nd day on it. If its still this way after a few weeks on a stable dose, I would quit it. In my opinion its much too early to draw any conclusions at all. Epival does much more than just increasing gaba. It also blocks Na channels etc. ...
I guess you feel the antimaniac effect of it.just an example:
...valproic acid (VPA), has a very wide spectrum of clinical activity ...
"Valproate modifies spontaneous excitation and inhibition at cortical synapses in vitro."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14573383&dopt=Abstract
Roland
poster:rod
thread:304437
URL: http://www.dr-bob.org/babble/20040122/msgs/305254.html