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Re: nardil: » craig allen

Posted by Questionmark on September 15, 2003, at 20:33:48

In reply to nardil: will irritability increase at higher dose?, posted by craig allen on September 14, 2003, at 8:55:17

> i started on nardil almost 5 weeks ago. one week at 30mg, two at
> 45mg, coming up on 2 weeks at 60mg. i first noticed that i was more
> irritable at 45mg during the second week. at 60mg it's been worse,
> although somewhat better than the first week at 60 i think. i'm
> pretty sure i've read that people get more of an anti anxiety effect
> at doses more in the 75 - 90 range. is this true? if so, i'll push
> my dose. my fear however, is that i'm going to get even more
> cranky. i should also note that i am doing better on nardil,
> increased irritability aside. i have more energy, i'm more inclined
> to be social. since i'm still relatively new on the drug, i'm
> hoping i'll continue to improve. any advice on what to do with my
> dosage at this point would be greatly appreciated.


Hey. i would remain at 60mg for awhile, especially if you're doing well aside from the irritability. The thing is, every time you increase the dose, it can take awhile (even up to several weeks i believe) for your neurons/ receptors to adapt, so if one is increasing the dose every week or so, s/he might not be able to determine if the effects are stable or if they're just from temporary adaptation. For instance, i was doing well on 45mg for a couple weeks, and then since i upped to 60 last week i have been feeling worse. i'm not sure if it's the med or just me i dunno, but i'm gonna wait and see if it gets better & then decide whether to stay or go back to 45. Anyway that's my advice. Good luck.


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