Posted by dr. dave on November 6, 2002, at 3:59:59
In reply to Re: Lexapro 'failed' trial: I get confused, posted by JLM on November 6, 2002, at 3:23:31
I have no doubts that Lexapro is an efficacious and very well-tolerated antidepressant. The point I am trying to make is that the information presented to the general public, and medical practitioners for that matter, is often very misleading. I think that in a population including lots of people with milder forms of depression, the advantages of antidepressants over placebo are a bit slim. However, if you look at people with more severe depression I think the advantage over placebo increases to something really significant.
The idea that Lexapro has the same side-effect profile as Celexa has been vigorously disputed on this board, but as the data has come out the claim has been dropped. It has also ben claimed that there have been nine 'positive' studies and no negative studies. When we look into it there is at least one 'failed' trial, and I'm not sure where all these nine trials are.
I have no doubt Lexapro works and is a good drug - it's just that we're all being misled about it.
poster:dr. dave
thread:109458
URL: http://www.dr-bob.org/babble/20021101/msgs/126641.html