Posted by freedom2001 on November 6, 2002, at 1:14:50
In reply to Re: AUGMENT PROZAC OR SWITCH SSRI » freedom2001, posted by hiba on November 6, 2002, at 0:29:44
> I am taking prozac for depression which was a consequence of severe obsessive rumination. So my diagnosis will probably be Obsessive depression, or depression with obsession.
I think the correct term should still be OCD, as it is the obsession that is the primary factor that causes the depression. I have exactly the same condition as you. The thing is, if our obsessions are gone, the depression will lift up automatically.
I began on 20 mg daily and it was helpful for sometimes. But gradually I lost the grip and had to double the dose.
For severe rumination, you need to up your dose to 60-80 mg. This is the dose to tackle OCD.
>
> I have tried pindolol at the initial stages and it definitely had an augmenting effect.I think it lifts your depression, but not the OCD. According to studies that I read, pindolol lifts depression, but is not anti-OCD to be precise.
Correct me if I'm wrong.
The caution should be exercised when you switch to another drug, because the new drug shouldn't necessarily be as effective as the old one.
Agreed. I don't think celexa or any other drug is guaranteed to be more effective than prozac.
Besides prozac takes a long time to have an effect and this duration could be much longer for the second time. It is my experience.
What do you mean? you mean when you switched from prozac to another SSRI and back to prozac again, it takes much longer for the 2nd trial of prozac to have any effect?
This is important to me.
> Tofranil, as a tricyclic will augment the effects of prozac but I don't think anafranil (clomipramine) is a good choice. Though a tricyclic, anafranil mainly targets serotonin and adding it to SSRIs will probably cause a serotonin syndrome.
What does tofranil target and how does it augment prozac?
Prior to SSRIs Anafranil was the treatment of choice for OCD and still it is being hailed as the most effective OCD medication. But anti-cholinergic and sedative effects make its clinical indication lesser than SSRIs. If you are ready to bear those bothersom anti-cholinergic and sedative effects you can switch to anafranil with the consent of your treating physician. It is a highly effective OCD medication.
> HIBA
poster:freedom2001
thread:126376
URL: http://www.dr-bob.org/babble/20021101/msgs/126633.html