Posted by pharmrep on October 16, 2002, at 15:36:26
In reply to Re: 20%? » Gaillardia, posted by pharmrep on October 16, 2002, at 14:20:35
> What's the figure going to be on Lexapro..2%?
> >
> > As a psychotherapist (social worker)I routinely ask about s/e to SSRI's. I routinely ask "any sexual problems?" I have strong opinions about the numbers given, and have argued with many doc's abt the true rates of sexual s/e related to orgasm/ejaculation problems and reduced sex drive. Anecdotally, I find the rate of sexual s/e's to be at least 80% to any given ssri, with Effexor perhaps being slightly lower. I want to learn much more abt these new meds for my clientele! SSRI's have changed and saved millions of lives, I expect, although I agree with the studies that indicate antidepressants aren't longterm effective without therapy. Anyone left out there reading this? Any thoughts? --Gail
>
> ** The Lexapro study donelast year showed 9%.. is that a bid selling point? No. Sexual s/e are a class effect, only Paxil seems to be a little worse than the rest (prozac/celexa/zoloft/effexor all seem to be about the same...including lexapro so far) The "volunteered" info from the FDA studies from 10+ yrs ago were grossly off since it was not commonly shared for whatever reason. so the 6% -12% range was more like 25%-50% in reality...whether the 9% from just 1 year ago for lexapro holds up (since the topic is hot and the info more readily shared) has yet to be seen...I imagine it will be higher, but not as bad as paxil...it will take time to see, but this is not at all the selling point...the greater efficacy, increased potency, quicker onset of action, s/e and discontinuation due to adverse events comparable to placebo, and least expensive branded ssri are the selling points.
>
> (ps..I know the meds are involved, but have you considered the pre-existing % of sex s/e?...80% seems a little high.)*** i said "selling point" not just point in general. I know this is a tough se to work with, and that it is a "class effect"...I was saying that the other ssri's have the same challenge and that there are other ways lexapro separates itself from them. sexual side effects is not the main selling point.
poster:pharmrep
thread:109458
URL: http://www.dr-bob.org/babble/20021012/msgs/123906.html