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Re: Protein Folding and Prions » Randal

Posted by IsoM on August 26, 2002, at 0:41:42

In reply to Re: Supplements, Jokes, and a Question » IsoM, posted by Randal on August 25, 2002, at 22:37:40

I followed Dr. Stanley Prusiner's initial ideas about the causes of diseases like kuru, CJD, & scapie with interest when I first read about it in the early 90s. I remember how his ideas about prions was discounted by some in the scientific community. I'm glad he won the recognition & credit he deserved. It was his ideas about prions that first sparked my interest in protein folding. Interesting now that prions aren't all thought to be aberrant, but some are thought to have a purpose. Things are rarely as simple & clearcut as they may appear at first.

If I have difficulty in getting hold of any of the articles you mention (thanks for the links), I'm on good terms with the head of the biology department at the nearby u. & she'd help me get them. I knew (but forgot) that part of the polypeptide chain can already be folded while part of it is still coming off the ribosome.


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