Posted by pharmrep on July 31, 2002, at 21:30:49
In reply to Re: Captain Mitch and the downers, posted by pharmrep on July 31, 2002, at 20:46:51
I need to be brief, so I hope this helps several of the last threads.
Poop out? if this means patent..Celexa is not going to have a generic
available for 3 years. Sex side effects..anorgasmia, ejaculatory delay,
impotence, ED, decreased libido, etc. Celexa showed 6%, (ejac delay only) but was more like
20%. This is a tricky one...the doctors dont ask the patients the question,
it is volunteered (5+ yrs ago (pre-viagra..etc) nobody wanted to admit it, now
it is much more open. All ssri's deal with seratonin, so it cant me avoided, but the
more selective, the less the effects...ie, Celexa only needed to list ejac delay since
greater than 5%, the other side efx are less that that. early Lex studies show good
promise in this arena. 9%, and this is a more accurate read since people are more willing
to talk about it, but maybe teens will be reality, only time will tell.
Celexa is indicated 20/40/60 mg. 20 is used 62%, then 40 is the next 30%...60 and higher is usually
for major dp or ocd component. Lex will be 10/20 mg 10 is starting and maintenance dose, and will
be for most. Early studies show 10/mg Lex is slightly more efficacious than 40mg/Celexa, as early of
an onset as 1-2 wks for most. (Journal of Clin Psych 2002; 63:331-336 by William Burke.
Sorry, I cant give cost analysis for everywhere other than Lex will be slightly less than Celexa.
LLL, are you 5'2" or so and in So. Cal? Anyway, the initial studies are showing efficacy, head to head vs.Celexa and placebo, and anxiety..I'm sure other head to head and others will come. I know that other indications have
already been filed too. Another good study by Burke is more about stereoisomers (journ. Clin Psych 2002;4(1)
poster:pharmrep
thread:109458
URL: http://www.dr-bob.org/babble/20020731/msgs/114709.html