Re: Mix a 5-HT1a agonist with a 5-HT2 antagonist?

Posted by cybercafe on July 11, 2002, at 9:14:43

In reply to Mix a 5-HT1a agonist with a 5-HT2 antagonist?, posted by Shawn. T. on July 11, 2002, at 7:16:31

> I believe that you could mix the new potent 5-HT2 antagonist M,100,907 with a 5-HT1a agonist like gepirone to achieve good effects. Nausea may cause a problem, however. Adding a 5-HT3 antagonist or using a 5-HT2/5-HT3 antagonist might solve that if it becomes a problem.
... wait a sec... if you cause the 5TH1a receptor to fire, isn't that like saying "there is too much serotonin in the synapse, please do not release more" .... which means both the presynaptic and postsynaptic neurons won't fire??

Thread

Mix a 5-HT1a agonist with a 5-HT2 antagonist? Shawn. T. 7/11/02
I forgot to cite a nice source for this idea Shawn. T. 7/11/02
Re: Mix a 5-HT1a agonist with a 5-HT2 antagonist? cybercafe 7/11/02
Re: Mix a 5-HT1a agonist with a 5-HT2 antagonist? Shawn. T. 7/11/02
Re: Mix a 5-HT1a agonist with a 5-HT2 antagonist? cybercafe 7/12/02
Re: Mix a 5-HT1a agonist with a 5-HT2 antagonist? Shawn. T. 7/14/02

Post a new follow-up

Notify the administrators

Start a new thread

poster:cybercafe thread:112023
URL: http://www.dr-bob.org/babble/20020709/msgs/112030.html

	for
in