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Re: MAOI dexedrine

Posted by Psydoc on June 22, 2002, at 6:06:04

In reply to Re: MAOI dexedrine » Psydoc, posted by michael on June 22, 2002, at 4:57:27

> Dr. Goldberg,
>
> Thank you very much for your above response to my previous question. If you (or anyone else here…) can spare the time, I have some quick follow-up q’s …
>
> [1] What is considered a "full dose" of parnate?

A fulldose of Parnate is about 130 mg/day. Please see: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2710808&dopt=Abstract

>
> [2] Would the addition of Dexedrine to parnate make sense only if there was at least a partial response to the parnate alone?

I generally add Dexedrine when the dose of Parnate (or another MAOI) cannot be increased any more because of the severity of side-effects, and significant depression remains. Only then do I add Dedxedrine, Ritalin, or Wellbutrin.
>
> In my case, I'm currently taking 60mg Parnate (30mg bid) w/little response... I worked up to 20mg Dexedrine (which has been my usual dose either alone or as an augmenter) on top of the parnate, with no problems. [& no significant difference from dex by itself]
>
> [3] Would increasing the parnate dose (to 80mg? or a "full dose"?) monotherapy (i.e. w/o the Dexedrine) be an advisable/logical next move to discuss w/my pdoc?

If I had a partient who came to me taking Parnate and Dexedrine in doses similar to the ones you mention, I would probably slowly increase the Parnate, rather than stop the Dexedrine and then increase the parnate.

Best regards . . .

Ivan Goldberg
psydoc@psycom.net
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