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Re: Desyrel (Trazodone) experiences ? -questions » ben

Posted by cmcdougall on May 5, 2002, at 17:40:24

In reply to Desyrel (Trazodone) experiences ? -questions, posted by ben on May 4, 2002, at 13:01:13

Dear Ben,

> Who has some experiences with trazodone ? I tried many ADs and my pdoc considers to try it. How is sedation comparing to other ADs ?

I've taken trazodone for years... It was the first AD I ever tried and was effective but I had to keep increasing the dose. It is VERY sedating. Only 50mg will make most people very drowsy. I eventually got up to 350mg per night and had a lot of trouble waking up in the morning. When the time came to increase the dose again, there was no way. Thats when I switched to Serzone. During the 2 years I was on Serzone, I didn't take any trazodone. I titrated down pretty quickly and experienced absolutely no withdrawal. Never had any trouble falling asleep either. My pdoc explained that a proper therapeutic dose of trazodone is very high - 400mg or more per day. That dose is so sedating that when it is used as a stand-alone AD, the patient is usually being treated in hospital.

> Can it be combined with Venlafaxine (efexor) and could it be a good combo

When my Serzone pooped-out, I started taking Effexor. The Effexor was very activating and I had a lot of trouble falling asleep. My pdoc again prescribed trazodone, but only 50mg at night. I never had ANY problems combining the two.

I now take Celexa, Adderal, desipramine, AND 50mg trazodone every night. Very rarely I will take 100mg if I'm too hyper to settle down properly.

IMO, trazodone is a great sleep aid that is safe to take in combination w/ other ADs. It is not addictive and I don't believe that a tolerance to its effects is common.

Love and luck,
Carly


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