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Re: Increasing clonazepam dosage » Squiggles

Posted by JohnX2 on April 7, 2002, at 21:29:36

In reply to Increasing clonazepam dosage, posted by Squiggles on April 7, 2002, at 18:44:24

> Hello,
>
> For those who do not remember me (i did try
> to post few days ago), I have residual withdrawal
> effects from clonazepam. It was a long withdrwal
> (1 year plus) culminating in a seizure or stroke
> or aneurysm - never clearly recognized by the
> doctors; anyway, my doctor gave me free reign
> to increase the dosage as i felt necessary; it
> was reinstated to the initial 1.0, but with the
> withdrawals continuing, i took it up to 1.125 and
> still feel some. I am wondering if I should
> increase it still more.
>
> I welcome answers from people who have actually
> been through benzo withdrawal as it it seems
> a controversial and mysterious matter for those
> who have not.
>
> Thank you.
>
> Squiggles

Squiggles,

Sorry to hear about such a horrendous experience. Klonopin is an antiseizure medicine, and it was studied for the use in epilepsy but was found to be ineffective due to the potential for rapid tolerance developed to ints anticonvulsant effects. I believe for vanilla anxiety treatment, its anxiolytic effects are less likely to wear off/poop-out.

Anyways, I was a strong klonopin addict, using it to treat myofacial pain. I started at 2 mg and finished at 6 mg. I couldn't find a suitable medicine to replace it, until I stumbled on Topamax. Topamax is also an antiseizure medicine, but it is not habit forming (won't give withdrawl seizures, I don't believe) and it almost immediately relieved most of my pain symptoms. I was able to taper 4 of the 6 mg of Klonopin in about 6 weeks without much pain. Topamax increases the conductance of GabaA neurons, just as Klonopin does (I don't know of another antiseizure medicine that increases chloride conductance through GabaA neurons).

Don't know if this information would be useful...need to talk to a really good neurologist.

Please take care.

John


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