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Re: Has anyone lost weight while taking Pamalor? » genelowery

Posted by SalArmy4me on September 12, 2001, at 19:09:08

In reply to Has anyone lost weight while taking Pamalor?, posted by genelowery on September 12, 2001, at 18:07:18

Nortriptyline primarily inhibits the reuptake of noradrenaline. Increased noradrenaline activity increases food intake. Tricyclic antidepressants may also block the role that histamines play in the inhibition of appetite and may reduce the resting metabolic rate.

Desipramine (very similar to nortriptyline), on the other hand, may not have this problem. Neither does reboxetine (similar site of action in the brain).


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