Posted by Elizabeth on September 8, 2001, at 21:52:02
In reply to Re: Foreign Medications, posted by SLS on August 31, 2001, at 19:26:57
> You might be right about the DA, although I believe it is thought that reuptake inhibition is negligible at therapeutic dosages.
That could be a marketing claim. (They also said that Xanax wouldn't cause dependence, you know. < g >)
> Who knows? I often wonder how it is determined the amount of anything that can be neglected.
Trial and error?
> I was sure I was on my way to Jamaica.
I hope you don't mean this literally. :-)
> It was like Dorothy opening up the door of her black-and-white house to the rush of technicolor that was Oz.
Heh -- I've made that analogy (I'm sure many others have too).
> I desparately and recklessly self-medicated in a frantic effort to get it back, and ended up in the hospital from a Nardil overdose. It wasn't so bad, although I was a bit upset that they didn't serve me sorbé to clear my palette before regaling me with charcoal.
Stuff's gross, isn't it?
> To my surprise, I felt terribly worse after discontinuing it - worse than I had before starting it.
It's called "withdrawal." :-) (Ever quit MAOIs abruptly? Same idea.)
> I still like the idea of selectively inhibiting MAO-A. I really don't care if it's reversible or not. With respect to inhibition of MAO-A, if comparing moclobemide to clorgyline represents a comparison between reversiblity and irreversibility, reversibility would equate to reduced efficacy.
Yup.
> Elizabeth, do you know where adinazolam is being sold? I tried it in 1984 or thereabouts. It was extaordinarily clean.
Interesting. How so ("clean," that is)? (I mentioned in a previous post that they have it in France and Germany, Switzerland too I imagine.)
> Unfortunately, I didn't respond to it. It was completely neutral, having none of the sedating or hypnotic effects of other benzodiazepines.
I've found many ineffective drugs to be "neutral" (Zoloft, Serzone, Lamictal, ...).
> Ultimately, he was surprised to see how many of his patients responded to it. I think it is interesting that both adinazolam and alprazolam are triazolobenzodiazepines and that both have demonstrated antidepressant properties. However, where does that leave Halcion?
Too much amnesia!
-e
poster:Elizabeth
thread:76877
URL: http://www.dr-bob.org/babble/20010907/msgs/78314.html