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Re: Going Crazy: Could it be Buspar????? » Mitch

Posted by Elizabeth on July 8, 2001, at 15:35:57

In reply to Re: Going Crazy: Could it be Buspar????? » AMenz, posted by Mitch on July 7, 2001, at 10:28:25

> I do know that it *reduces* serotonin and Zoloft which calms my temper increases serotonin.

?

Buspar imitates the action of serotonin at a particular site (the 5-HT1a receptor, believed to be involved in depression and some types of anxiety) -- it's what's called a partial agonist at this receptor. That doesn't mean it "reduces" serotonin.

If it was making your temper or mood worse to a point where you couldn't function, then it probably was best to go off it (without any need to speculate about the mechanism whereby it did this). What dose were you taking, and for how long?

-elizabeth


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URL: http://www.dr-bob.org/babble/20010708/msgs/69415.html