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Re: Amisulpride, Selegiline- Michael » AndrewB

Posted by michael on June 6, 2000, at 20:21:00

In reply to Re: Amisulpride, Selegiline- Michael, posted by AndrewB on June 5, 2000, at 23:47:44

Hey Andrew -

I did a bit or reading on the meds you mentioned... I had been wondering about levodopa as a possibility. Sounds interesting, if dopamine's the issue... Good Luck! I'll be looking forward to your "report".

The only other thing I would say is to be careful... Too much of a good thing (dopamine, in this case) might not be a good thing.

Isn't that (too much dopamine) what neuroleptics - like higher-dose amisulpride, etc. - are trying to address? Might psychotic symptoms be a side effect if carried beyond a certain point?

I've been wondering about that myself, since I've been experimenting w/low-dose amisulpride and selegiline...

One last Q for you... have you come across much/any rsch that specifically looks at dopamine (and its manipulation) as a focus in the treatment of depression/dysthymia? I haven't looked as of yet... Serotonin seems to get the lion's share of media attention... just curious. michael

> Thanks for the new info. on your amisulpride experience.
>
> Recently read a study abstract that indicates 5mg. of selegiline does the same as 10mg.
>
> Have you noticed any improvement on your seligiline, amisulpride combo.
>
> I've had nice results with entacapone as a dopaminergic agent of arousal. I want to wait until I get a chance to combine it with Sinemet before I say anything more about it though.
>
> AndrewB


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URL: http://www.dr-bob.org/babble/20000603/msgs/36361.html