Posted by Scott L. Schofield on April 21, 2000, at 13:20:36
In reply to Re: Mirapex vs. amisulpride, posted by AndrewB on April 21, 2000, at 11:12:50
> ...5% to 10% of women using amisulpride will quit using it due to endricrinological side effects like missed menses and breast swelling.
I wonder if these side effects appear as frequently when amisulpride is used at the lower dosages prescribed to treat depression. I believe that the increased secretion of prolactin that is responsible for them is the result of postsynaptic DA receptor blockade. Prolactin secretion is inhibited by postsynaptic DA agonists, such as Mirapex. Perhaps a combination of these two drugs, in addition to possibly effecting a synergism in promoting an antidepressant response, will reduce the potential for these neuroendocrine effects.
- Scott
poster:Scott L. Schofield
thread:29957
URL: http://www.dr-bob.org/babble/20000420/msgs/30844.html