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Dr. Bob is Robert Hsiung, MD,
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Posted by alexxf on July 20, 2007, at 12:11:58
I'm on zoloft (10 mg) and have been for a little over 2 months now, i keep trying to give it time to REALLY kick in, but it doesn't seem to have the same effect on me as it used to (years ago). (I went off it while i was pregnant then i was on lexapro). And now I've been taking provigil to help with the fatigue and just to help me be more alert during the day...But i feel like it REALLY just killed the zoloft. My anxiety is up, my mood swings are back, and i've been feeling more depressed. A pharmicist says it shouldn't be the mix of the 2 drugs doing this? Do i need something stronger for the depression and anxiety? Any suggestions?
I like the effects of the provigil so i don't want to decrease that, but i hate this "feeling" inside me (sad, lonely...)
thanks, Alex
Posted by alexxf on July 23, 2007, at 14:04:57
In reply to ZOLOFT + PROVIGIL...Depression getting worse..., posted by alexxf on July 20, 2007, at 12:11:58
CORRECTION: It's 50 mg of zoloft...it WAS 10 mg of lexapro...
Posted by florence on September 19, 2007, at 20:52:53
In reply to ZOLOFT + PROVIGIL...Depression getting worse..., posted by alexxf on July 20, 2007, at 12:11:58
I've taken Provigil on and off (mostly on) for over 5 yrs. My only health complaint was fatigue.
I researched Provigil yrs back- someplace I read and wrote down that Provigil can interact with Celexa (similar to Lexapro) - maybe decrease the wakefulness properties.Perhaps the same is true with zoloft (being an SSRI).
I never knew what anxiety was- until I started Provigil. So maybe the Provigil is causing the anxiety. Headache and anxiety are stated on the patient info sheet to be clearly related to dose.
I got both of these side effects from Provigil. On 100 mgs. and now at 4-600mgs. (Insane! I know)
Provigil abusers claim to be a big euphori from massive doses... but from the start I knew Provigil never helped mood...I almost feel like it overstimulates my brain and not my body.
It is a Controlled substance and I have learned the hard way that tolerance develops.
Another thought- my sister got shakey on zoloft; maybe cuz it affects dopamine a little.
I'm on zoloft (10 mg) and have been for a little over 2 months now, i keep trying to give it time to REALLY kick in, but it doesn't seem to have the same effect on me as it used to (years ago). (I went off it while i was pregnant then i was on lexapro). And now I've been taking provigil to help with the fatigue and just to help me be more alert during the day...But i feel like it REALLY just killed the zoloft. My anxiety is up, my mood swings are back, and i've been feeling more depressed. A pharmicist says it shouldn't be the mix of the 2 drugs doing this? Do i need something stronger for the depression and anxiety? Any suggestions?
>
> I like the effects of the provigil so i don't want to decrease that, but i hate this "feeling" inside me (sad, lonely...)
>
> thanks, Alex
Posted by SometimesBlue on September 20, 2007, at 8:46:56
In reply to Re: ZOLOFT + PROVIGIL...Depression getting worse..., posted by florence on September 19, 2007, at 20:52:53
I was told the same thing by the pharmacist, but i don't think it's true. My exact words to the pharmacist & my doctor were "i think the provigil killed the zoloft because all my old symtoms are back - and worse i think"...but they didn't think it was the mix of the 2 drugs, with the exception of the anxiety which they said could become worse with the provigil. So my doc switched me to lexapro which i thought made a difference. The anxiety got A LOT better and the depression got a little better but not too much.
And as far as zoloft, even when i was on it alone i never felt it helped. The first time i was on Lex it helped a lot, but it pooped-out the second time i was on it. I'm on Wellbutrin now and i think it's SOOOOOOOO much better than any AD i've been on yet. It's helped with fatigue, which is a side effect of most AD's. And while most people say it can make your anxiety worse, i don't think it did - and i usually have very bad anxiety attacks and panic attacks. However, i did notice than too high of a dose will give you anxiety/panic attacks (i was experimenting with myself - i know, dumb, dumb dumb!). But i always like to test the waters :p ***Hopefully this one will last***
Hope this helps,
SB (formerly alexx)
This is the end of the thread.
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