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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by Lamdage on June 26, 2011, at 8:06:34
Hey,
i was wondering about adding sth like for example huperzine A before bedtime to restore REM sleep and counteract some of the cognitive side effects?
A cholinergic agent that acts only a couple hours would be great for this i think. Maybe the cognitive side effects are a result of the lack of REM sleep.
Experiences/ thoughts on this?
Posted by BrainDamage on June 26, 2011, at 10:31:29
In reply to Nardil + cholinergic agent anyone?, posted by Lamdage on June 26, 2011, at 8:06:34
Most Choligenics make me feel like crap
There's also the risk of interactionHaving said that I like CDP Choline/Citocoline
I can't see how this could interact with Nardil-but you never know!
I would be very cautious..............
Posted by Lamdage on June 26, 2011, at 11:00:42
In reply to Re: Nardil + cholinergic agent anyone?, posted by BrainDamage on June 26, 2011, at 10:31:29
> Most Choligenics make me feel like crap
> There's also the risk of interaction
>
> Having said that I like CDP Choline/Citocoline
> I can't see how this could interact with Nardil-but you never know!
> I would be very cautious..............Okay, thanks i will keep that in mind! I think this is a general rule applying to everything taken or eaten together with nardil.
I cant see how a dangerous interaction should develop. Cholinergics did not make me feel that bad when i took em! Im just looking for ways to keep the cognitive brain functions up to par cuz i want to start studying next year!
Ps: got some choline here, acetyl-l-carnitine, too!Cheers
Ld
Posted by desolationrower on June 26, 2011, at 14:04:28
In reply to Nardil + cholinergic agent anyone?, posted by Lamdage on June 26, 2011, at 8:06:34
i think you'd want to take them during the day, when you are studying.
reduction in REM may be what is causing the antidepressant effect. most depressed people have to omuch.
-d/r
Posted by Lamdage on June 26, 2011, at 14:36:29
In reply to Re: Nardil + cholinergic agent anyone?, posted by desolationrower on June 26, 2011, at 14:04:28
So there is a such thing as cholinergics with emmidiate effect?
Posted by sigismund on June 26, 2011, at 16:10:25
In reply to Re: Nardil + cholinergic agent anyone?, posted by Lamdage on June 26, 2011, at 14:36:29
>So there is a such thing as cholinergics with emmidiate effect?
Yes. Centrophenoxine worked straight away. I only took it once. For a while it seemed interesting, but I never wanted to repeat it.
Then there is stuff like aniracetam, which wasn't so bad. Is that some nicotinic recptor thingo?
Posted by Lamdage on June 26, 2011, at 16:19:16
In reply to Re: Nardil + cholinergic agent anyone?, posted by sigismund on June 26, 2011, at 16:10:25
Why what was so bad about it? I would use it for extensive studying purposes and maybe every once in a while to get some rem sleep. Also i find this whole lucid dreaming thing interesting.
Ld
Posted by sigismund on June 26, 2011, at 18:11:27
In reply to Re: Nardil + cholinergic agent anyone?, posted by Lamdage on June 26, 2011, at 16:19:16
A friend had this system for gambling on horses. I became a bit kind of manic and ended up leaving my wallet in the TAB, so it didn't help my memory with that. And then I became excited and doubled the bet on the last horse and lost, and it was an important part of the system not to do that. Maybe it affected my judgement?
Posted by desolationrower on June 27, 2011, at 22:48:12
In reply to Re: Nardil + cholinergic agent anyone?, posted by sigismund on June 26, 2011, at 16:10:25
> >So there is a such thing as cholinergics with emmidiate effect?
>
> Yes. Centrophenoxine worked straight away. I only took it once. For a while it seemed interesting, but I never wanted to repeat it.
>
> Then there is stuff like aniracetam, which wasn't so bad. Is that some nicotinic recptor thingo?nicotine is pretty damn fast.
aniracetam does some other things like piracetam, but i think it agonise one or two of the nicotinic receptors
-d/r
Posted by SLS on June 28, 2011, at 5:20:01
In reply to Re: Nardil + cholinergic agent anyone?, posted by desolationrower on June 27, 2011, at 22:48:12
It is my understanding that certain nicotinic receptor antagonists, mecamylamine (Inversine) for example, can precipitate or exacerbate depression. Muscarinic antagonists, by comparison, can exert antidepressant effects. If biperiden (Akineton) is still available, that would be my choice of anti-muscarinic.
Maybe d/r can check me on this.
- Scott
Posted by desolationrower on June 29, 2011, at 0:03:39
In reply to Re: Nardil + cholinergic agent anyone? » desolationrower, posted by SLS on June 28, 2011, at 5:20:01
> It is my understanding that certain nicotinic receptor antagonists, mecamylamine (Inversine) for example, can precipitate or exacerbate depression. Muscarinic antagonists, by comparison, can exert antidepressant effects. If biperiden (Akineton) is still available, that would be my choice of anti-muscarinic.
>
> Maybe d/r can check me on this.
>
>
> - Scottall of that sounds right (i haven't heard of biperiden)
nicotine looks like an AD in animal tests, though i think there is some idea that (something?) alpha7? nicotinic receptor downregulation is important, and an antagonist would work too, similar to the 5ht2 role vis-a-vis ssris.
the only drug i have personal experience with is nicotine. the lozenges work almost as well as AMP for adhd for me.
-d/r
Posted by Lamdage on June 29, 2011, at 0:55:48
In reply to Re: Nardil + cholinergic agent anyone?, posted by desolationrower on June 29, 2011, at 0:03:39
not what i wanted to hear, im trying to kick this nasty habit!
Hm.. with nardils kickass antidepressant power i dont have to worry so much about something "depressing" every once in a while. Its just for occasional "powerstudying" xD.
This is the end of the thread.
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