![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by Vincent_QC on December 16, 2008, at 7:34:00
Hi everyone,
Since yesterday, i'm taking 20mg/day of Parnate and I have a "lot" of side-effects.First, with my own blood pressure machine, I notice that my pressure is not constant at all. My pulse is very low (40-50), normally it's up than 80 and my blood pressure is sometimes very low 100/50 and sometimes high 150/90. If I have to climbe the stairs, I begin to feel weird, having dizziness and I ending it with a panic attack. I also feel VERY tired, not when I take my pill, but often more after 2 or 3 hours. I feel like I will pass out or do a heart attack, I have arm numbless also, especially the left one, dry eyes (they burns in fact), and the list go on. And Strangely, contrary to some people on the Parnate on this board, I don't have more insomnia, I can sleep, even if it's in the middle of the afternoon...(I already have insomnia problem before at night, I wake up frequently and I can't fall asleep again).
It's seem that even if I watch what I eat or not, my pressure vary more on the Parnate than the Nardil.
20mg of Parnate is equal to how many mg of Nardil? Cause I begin to have pressure problems on the Nardil at 90mg only...
Is it possible that all is in my head??? Can i imagine all of this and make my blood pressure test distorted? Is it possible that my general anxiety make me feel worse than I am really?
I know that 20mg of Parnate is a very low dosage, probably not effective at this stage...So i'm wondering if it's just the anxiety or it's really my blood pressure that causing all these side effects?
Another question. Is it possible that the "COFFEE" make me feel like this? I drink 2 cups in the morning and 1 in the afternoon...
What is the best hours to take my pills, did I take the 20mg in the morning in one shoot, or I devide it in two shoots, one at 7-8 AM and another one before 3 PM?
Anyway's thanks in advance for all the answers I will have in regards to this message. I know, I can seem to be on the panic button...but that's not the case, I just feel really WEIRD and I have some side effects that make me feel more anxious, especially about my "heart"...the pressure and everything. I'm already in a "so so" physical shape, I smooke a lot, I don't eat well and I don't exercise, so that's easy to understand that i'm a lot concern about the blood pressure and everythings else...
Posted by desolationrower on December 16, 2008, at 10:11:10
In reply to Parnate + hypo/hyper-tension (SP-GAD), posted by Vincent_QC on December 16, 2008, at 7:34:00
Hey vincent
I had somewhat similar effects on parnate when starting, though not as bad
I split my dosage so 1 dose with breakfast, and then 1 in the afternoon when i would feel very tired. The dizziness i didn't find any easy answer for, but it passed...you may want to take just 10mg a day for a week or so, it sounds like body is not adjusting quickly enough...if you went right from nardil, then you didn't have the 'warm-up' period during which the MAO enzyme is being slowly lowered, so the parnate is able to have a strong effect right away...hope it gets better soon
-d/r
Posted by Phillipa on December 16, 2008, at 10:40:05
In reply to Re: Parnate + hypo/hyper-tension (SP-GAD), posted by desolationrower on December 16, 2008, at 10:11:10
I'm sorry this has happened to you although don't take Maoi's wanted to lend my support. Love Phillipa
Posted by Vincent_QC on December 16, 2008, at 23:05:53
In reply to Re: Parnate + hypo/hyper-tension (SP-GAD), posted by desolationrower on December 16, 2008, at 10:11:10
> Hey vincent
>
> I had somewhat similar effects on parnate when starting, though not as bad
>
> I split my dosage so 1 dose with breakfast, and then 1 in the afternoon when i would feel very tired. The dizziness i didn't find any easy answer for, but it passed...you may want to take just 10mg a day for a week or so, it sounds like body is not adjusting quickly enough...if you went right from nardil, then you didn't have the 'warm-up' period during which the MAO enzyme is being slowly lowered, so the parnate is able to have a strong effect right away...hope it gets better soon
>
> -d/rHi d/r ;-)
Well, you're probably right about the fact that I change from the Nardil right away to the Parnate, so my body is maybe responding more faster to the Parnate effect, since the enzymes was probably already destroy...I still don'w know if Parnate is more type A or B acting??? If I well understand, type B are more activiting??? Type A are more anxiolytic?... Since some doctors said it's a reversible MAOI, and some say that it's an irreversible MAOI...I'm my head, it's more logical to say that it's irreversible, since it can take more than 30 days before the body begin to produce again the enzymes.
Today I try something different, I take the whole 20mg in one shoot at 8AM...I had an appointment at 9 AM with my psychologist and I only take half of a 5mg/valium at the same time, normally I take the entire 5mg of valium in the morning. Maybe it was the fact that I was a lot busy with the psychologist and that I didn't have the time to think about the side-effects, but I was feeling more well today. I still have a lot of muscles spams and I still feel really tired.
Strangely, I was not able to sleep this afternoon. I do a long nap normally in the afternoon, to be able to stay awake in the evening. The same apply for tonight. I go to the restaurant with a friend, from 7 PM to 11:30 PM and I was tired all night long, so much tired that I had difficulties to "articulates" the words I wanted to say (I have this often since my benzo addiction, a kind of cognitive problem, difficulty to speak...that's disturbing me a lot).
Anyway's, I will continu with the 20 mg in one shoot in the morning, I will slow down on the blood pressure, I don't take it today, I will try to forget the machine I have, I think my general anxiety have a lot do to in the way I feel. My day are not a lot busy, so I have a lot of times to think about my problems and all the little sensentions I feel inside my body. Yeah, I probably feel more the DA or NE effect od the Parnate right now but I think I will have to give my body a more long time to adjust to the dose.
I will stay at 20mg, until I feel good and the side-effects will fade away and when I will up the dosage to 30mg, I will split the dose half in the morning and half in the afternoon. That's sound more good like this no?
So again, thanks for your advise ;-) Humm BTW, the "TIRED" sentation, is it normal??? It will fade away also? It will be worst each time I increase my dose or what?
The Parnate remember me a lot the "Prozac" experience I had. On that drug, I was feeling a lot anxious and energic at the same time but also a lot tired...I know, it sound strange but I was just not feeling good...But with the Parnate, it seem to just affecting my general anxiety and my panic attack problems...The Parnate don't affect my social life, I mean it's not worse than before I begin it...With the Prozac I was not able to go outside the house...
Anyways, that's another story...lol
Thanks again!
Posted by mav27 on December 18, 2008, at 1:56:21
In reply to Re: Parnate + hypo/hyper-tension (SP-GAD) » desolationrower, posted by Vincent_QC on December 16, 2008, at 23:05:53
For me 10 and 20mg made me very tired. 30mg though (in one dose) felt more like i was on speed or something.
Posted by Vincent_QC on December 18, 2008, at 7:10:50
In reply to Re: Parnate + hypo/hyper-tension (SP-GAD) » Vincent_QC, posted by mav27 on December 18, 2008, at 1:56:21
> For me 10 and 20mg made me very tired. 30mg though (in one dose) felt more like i was on speed or something.
Hi...thanks for your answer ;-)
Yeah, it's what I experience right now. If I devide my dose in 10mg AM and 10mg before 3 PM, I feel really tired behind the two doses and after the last dose also. At night I have to be very motivated to do something, and often, like last night where I was suppose to go out with a friend, I just call him and cancel what we plan to do and I stay home watching TV...but strangely, I don't sleep well at night, I continue to have insomnia, even if I felt tired all night long...like I will fall asleep always.
If I take the 20mg in one time, I feel very energic for 3 hours, I can do 5 things at the same times without lacking the energy...but after I feel really tired as hell (remember me the time I was on Cipralex...always tired, like I work for 20 hours in a row) and the rest of the day is hard to finish without having to do a LONG nap in the afternoon...
For the side-effects, it's seem to fade away with time. I don't feel now the "panic" and the anxiety I had the first day at 20mg. I don't take my blood pressure like I was doing before...Too much is like not enought no?...and I stop watching what I eat, I just avoid cheese...for the rest I don't care. I even eat a couple of times some protein podwer with creatine inside without having a hypersensitive reaction. I plan to do a strict diet after the christmas period so it will be helpfull since I just can loose weight only if I do a strict diet (by-pass surgery history).
Anyway, I think all the side effects I had the first day at 20mg was related to my general anxiety problem, I can't find the button to shut off my brain!!! lol
I like the energic feeling of the Parnate when I take the 20mg in one dose. And like you write in your message, it's similar to the speed or at least an amphetamine effect. Speed and exctasy make me feel really anxious...yeah, I try both of them, I admit it and i'm not shy of this. I had a crazy experience of 6 hours of panic attacks in a row on them, back in 2005. I had big waves of anxiety, I was able to feel the panic attacks comming...and in my head I was like (Ho no, not again, I will do another panic attack...lol). I was completly exhausted after this experience and it was the last time I take street drugs of my life...
Anyway, the effect of 20mg of Parnate in one shot remember me the little boost of a 15mg of Ritalin, without the anxiety feeling and the moist hands and feets. I imagine that at the 60mg dose target, I will have to devide my dosage in 3x20mg...I will try to take 20mg when I wake up, 20 mg after luch time and 20mg before the diner... I don't care about the 3 PM hours limit and insomnia problem, cause I already don't sleep a lot and i'm use to sleep even if I drink a lot of coffee at night... My insomnia is related to my anxiety...I fall asleep fast but I wake up too much early and I begin to think about a lot of things in my head and I can't fall asleep again and I can't stay in my bed, I need to move, so I open my laptop, I open facebook, take my emails, make some laundry...things like that. I think i'm more productive at 5 AM than at 5PM !!! lol
Anyway, I have to stay at 20mg until december 31. My new psychiatrist is very strict on the dose, and give me a prescription with the exact count of pills I need until I meet him again the 14 january. Normally I will increase my dosage more faster than this but well, with him it seem that I will not able to do this...
I have one question for you...Did you feel a little bit of hypotension already at 30mg? Like when you climb the stairs or when you get up fast??? I have hypotension problem since I increase the dose at 20mg... I had this problem on 90mg of Nardil only...
My psychiatrist told me that the Parnate was causing less hypotension effects than Nardil...but for what I experienced at day 4 on 20mg of Parnate proove me that is not right about this fact. I have a prescription filled with a drug for the prevention of hypotension, I don't remember the name of that particulaf drug but I think I will have to begin to take it more soon that I Was thinking...It's the reason why I ask you this question, maybe at 30mg it will be worst for hypotension?. I hope not...
Well thanks again for sharing your experience with me ;-) And again, sorry if I write a LONG text for nothing...
Have a good day ;-)
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.