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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by bertill33 on April 22, 2004, at 1:56:02
What does pindolol augment? I have heard it is only SSRI's but I am on wellbutrin
Posted by chemist on April 22, 2004, at 2:13:07
In reply to Pindolol, posted by bertill33 on April 22, 2004, at 1:56:02
> What does pindolol augment? I have heard it is only SSRI's but I am on wellbutrin
hello there, chemist here....pindolol is a beta blocker and is currently used (off-label) to augment ssris, among other things....we are talking way different mechanisms of action, although i have not seen any lit. in re: wellbutrin and this drug........all the best, chemist
Posted by SLS on April 22, 2004, at 6:57:22
In reply to Re: Pindolol » bertill33, posted by chemist on April 22, 2004, at 2:13:07
> > What does pindolol augment? I have heard it is only SSRI's but I am on wellbutrin
> hello there, chemist here....pindolol is a beta blocker
Hi chemist.I think it is the 5-HT alpha-1 antagonist properties of pindolol that are thought to facilitate whatever adjunctive value it might have.
The way I read the early literature regarding pindolol was that it didn't so much augment the antidepressant response as it did produce an improvement earlier in treatment. They used the term "hasten the reponse".
- Scott
Posted by SLS on April 22, 2004, at 7:17:47
In reply to Re: Pindolol, posted by SLS on April 22, 2004, at 6:57:22
Sorry for the mix-up.
> I think it is the 5-HT alpha-1...Should be "5-HT1a"
- Scott
Posted by linkadge on April 22, 2004, at 7:24:04
In reply to Re: Pindolol, posted by SLS on April 22, 2004, at 7:17:47
Thats right pindolol is a 5ht1a presynaptic autoreceptor antagonist.
Linkadge
This is the end of the thread.
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