Grapefruit Juice Warning

Posted by Simus on May 27, 2004, at 0:37:10

In reply to Re: Hey trucker, posted by trucker on May 26, 2004, at 8:48:01

PLEASE READ THE FOLLOWING BEFORE DRINKING GRAPEFRUIT JUICE WHILE ON MEDICATION!!!
(I don't know if this includes a complete list of drugs affected by grapefruit. If you want to go on the grapefruit juice diet, you may want to check into this further).
From DRUGSTORE.COM:
"Drinking just one glass of grapefruit juice or eating a single grapefruit can significantly interfere with the body's ability to eliminate certain drugs. So these drugs may be present at higher-than-normal levels, which can increase the risk of drug side effects. This interference occurs even when these drugs are taken several hours after a grapefruit snack. Other citrus juices such as orange juice don't affect drugs this way.
Following is a list of common medicines that can interact with grapefruit juice. If you regularly take any of these medicines and also eat grapefruit or drink grapefruit juice, don't make any changes to your medicines or current diet. Instead, contact your doctor or pharmacist for advice.
Benzodiazepines, especially triazolam (brand name Halcion) and alprazolam (Xanax).
The calcium channel blockers felodipine (Plendil) and nifedipine (Adalat CC, Procardia). Similar drugs, such as diltiazem (Cardizem) and amlodipine (Norvasc), are only slightly affected by grapefruit juice.
HMG CoA reductase inhibitors ("statins") for high cholesterol, especially lovastatin (Mevacor) and simvastatin (Zocor).
Cisapride (Propulsid).
Ergot drugs for migraines, including dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), ergotamine (Bellergal-S, Cafergot), and methysergide (Sansert).
The immune system suppressants cyclosporine (Sandimmune, Neoral) and tacrolimus (Prograf).
Protease inhibitors, such as indinavir (Crixivan), nelfinavir (Viracept), and saquinavir (Invirase).
Sources:
Hansten, P.D., J.R. Horn. Drug Interactions Analysis and Management. Applied Therapeutics, 1999.
The Johns Hopkins Complete Home Encyclopedia of Drugs. Medletter Associates Inc., 1998.
Micromedex Healthcare Series. Micromedex, Inc., 2000."

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Grapefruit Juice Warning Simus 5/27/04
Re: Grapefruit Juice Warning Simus 5/27/04
Re: Grapefruit Juice Warning Anakin 5/27/04
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RE:: Hey yo yo's mystic 5/27/04
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RE:: Hey yo yo's trucker 5/27/04
Re: Grapefruit Juice Warning trucker 5/27/04
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Re: Grapefruit Juice Warning Magdalena 5/27/04
RE:: Hey yo yo's » trucker Simus 5/27/04
Re: Grapefruit Juice Warning Simus 5/27/04
Re: Grapefruit Juice Warning-simus anxious babe 5/27/04
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yo's have moved on to bigger and better things!:) (nm) NewWife 10/28/04

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