Posted by Phidippus on November 22, 2009, at 13:51:22
In reply to Re: calling all armchair psychs, posted by g_g_g_unit on November 21, 2009, at 18:32:52
its chemical structure is more closely related to cocaine. amphetamine works as a dopamine transport substrate where as methylphenidate works as a dopamine transport blocker.
Methylphenidate has both DAT and NET binding affinity, with the dextromethylphenidate enantiomers displaying a prominent affinity for the norepinephrine transporter. Both the dextro- and levorotary enantiomers displayed receptor affinity for the serotonergic 5HT1A and 5HT2B subtypes, though direct binding to the serotonin transporter was not observed.
poster:Phidippus
thread:924919
URL: http://www.dr-bob.org/babble/neuro/20091104/msgs/926547.html