Posted by bleauberry on December 11, 2008, at 17:13:49
In reply to Ixel and fatigue, posted by Applefreak on December 6, 2008, at 17:03:57
Sorry for a late reply. This forum doesn't appear to get much traffic compared to the med forum.
You might try dosing the Ixel at different times. Take a larger dose early in the day, a smaller dose later. Take the last dose no later than 3:00 in the afternoon. Maybe take the entire day's dose all at one time, experimenting with daytime versus night time. I found dosing times to have a large effect. My best times were 9am and 3pm, even though I start the day at 5am and start work at 7am. I waited until 9am for the first dose. Then instead of waiting a full 12 hours for the next dose, I would do it in mid afternoon, just 6 hours after the first dose. During one trial I even took the whole dose all at once in the morning and that worked good, except there was always a slight withdrawal type hangover the next morning until the next dose kicked in.
I think if you take the last dose too late in the day, you have too much norepinephrine happening when you go to bed at night. Since that keeps you from sleeping well, then of course you are tired and sleepy during the day.
If I took just the right amount during the day, I felt a slight stimulation. If I took too much, I felt kind of tired.
And it could be your dose is higher than it needs to be. You can't go by what the instructions say or by what works for someone else or by what they used in clinical studies. You have to take a dose that YOU tolerate, not someone else. Take a dose you can tolerate, in a dosing schedule that works for you, and then the longer you stay with it the better you should get. Low doses do work, they just take longer. I found that even 18mg, not even a whole 25mg capsule, was my best dose.
poster:bleauberry
thread:867082
URL: http://www.dr-bob.org/babble/neuro/20080706/msgs/868143.html