Posted by Amigan on August 18, 2008, at 13:07:15
In reply to Re: Is Mirtazapine really a NaSSA?, posted by undopaminergic on August 10, 2008, at 7:39:41
> Blockade of presynaptic alpha2-receptors accounts for some of mirtazapine's serotonergic effects, as some alpha2-receptors are located on serotonergic nerve terminals and act to inhibit serotonin release.
I see now. I think that what you have described here could explain why Clonidine has depressogenic properties and why some pure noradrenergic drugs can be useful for depression?
poster:Amigan
thread:841595
URL: http://www.dr-bob.org/babble/neuro/20080706/msgs/847019.html