Posted by linkadge on June 22, 2005, at 17:51:19 [reposted on June 22, 2005, at 21:03:38 | original URL]
In reply to Re: Excercise, dopamine and seratonin, posted by Declan on June 22, 2005, at 16:57:39
You may be right:
http://www.bio.davidson.edu/programs/HHMI04/summermentor.html
Aerobic exercise increases central dopamine concentrations and these increases are positively correlated with exercise output. Chronic exercise leads to the sustained release of dopamine and to subsequent reductions in the density of dopamine D2 receptors. It is not known whether these decreases in receptor density have functional consequences for sensitivity to psychomotor stimulants (drugs that activate central dopamine pathways to produce a host of behavioral and physiological effects). The purpose of this project is to examine the effects of exercise on sensitivity to the psychomotor stimulant cocaine in the conditioned place preference procedure, a procedure that measures the conditioned rewarding effects of drugs with abuse liability. In the proposed study, male and female rats will be obtained at weaning and reared either in standard laboratory cages or modified cages equipped with running wheels. After 6 weeks under these conditions, the conditioned rewarding effects of cocaine will be examined in both exercising and sedentary subjects, with particular attention placed on potential sex differences in these effects. A summer research assistant will be responsible for the care, training and testing of all research subjects. In addition, it is expected that the assistant will contribute to the analysis and preparation of the data for publication
----------------------------------------------It is quite possable that it has a ballancing effect on the serotogenic/dopaminergic axis.
Linkadge
poster:linkadge
thread:517292
URL: http://www.dr-bob.org/babble/health/20050411/msgs/517297.html