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Re: Larry Hoover - Niacin and Tolerance » karl

Posted by Larry Hoover on April 11, 2009, at 16:51:35

In reply to Larry Hoover - Niacin and Tolerance, posted by karl on April 10, 2009, at 0:54:14

> Hey Larry,
>
> If one feels Niacin to be effective, can one expect tolerance to develop as it does with benzodiazepines? And if so, is there a withdrawal form it?

I'm going to presume that you're really referring to niacinamide. It's the anxiolytic form of vitamin B3.

I don't know the answer to your questions. However, understanding the way the GABA-A receptor works, how it is regulated, and so on, I would have to assume that the answer is yes to both questions.

Frequent use of niacinamide will lead to adaptation to it (tolerance). After adaptation has occurred, ceasing exposure is going to lead to reversal of that adaptation (withdrawal).

That's my considered opinion, anyway.

Lar

 

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poster:Larry Hoover thread:889759
URL: http://www.dr-bob.org/babble/alter/20090410/msgs/889995.html