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Re: sam-e with prozac?

Posted by Declan on July 26, 2005, at 19:05:58 [reposted on July 28, 2005, at 19:41:35 | original URL]

In reply to Re: sam-e with prozac?, posted by med_empowered on July 26, 2005, at 18:03:08

I've taken 400mg SAMe/d for ages and it's been OK. Recently I started 10mg/d Parnate with it first thing in the morning. Day 1 was great, but by day 3 I was feeling agitated (rather than anxious ie benzos didn't help much).

When I cut out the SAMe the agitation went away.

Linkadge suggested that SAMe was fairly dopaminergic in effect. I had wondered if I was getting too much seratonin in some agitating receptor subtype. I thought this because Parnate had an immediate seratonin feel as well as the dopamine feel that I am more familiar with from deprenyl.

I've no idea how this might apply to Prozac (I've never taken it), but I thought you might be interested anyway.

Jessers1128, (is that name right?), was going to use SAMe with Cymbalta, I think. I dunno how it has gone with her.

Declan


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URL: http://www.dr-bob.org/babble/alter/20050713/msgs/535005.html