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Re: High LDL and Triglycerides » gromit

Posted by raybakes on November 12, 2004, at 11:31:16

In reply to High LDL and Triglycerides, posted by gromit on November 11, 2004, at 1:23:18

> Eeep, I just got results back from a blood test. Total cholesterol was 222 but triglycerides were 450. They were unable to figure out my HDL level since the triglycerides were so high! I had my last test less than a year ago, HDL level was a little low, but total was 170 or so. What would cause the levels go to up so quickly?
>
> I'm going to keep the fish oil, add more fiber and soy protein. More aerobic exercise. What else have people tried that worked for them? Anyone tried the "functional foods"? Had any luck with them?
>
>
> Thanks
> Rick
>

Hi Rick,

high LDL and triglycerides could be part of a syndrome X picture - insulin raises the activity of the rate limiting enzyme in chloesterol production (HMG CoA reductase). So it would be interesting to see what your insulin levels are like. Vitamin D, fish oils, CLA, tocotrienols, lipoic acid and soluble fibre are all useful in insulin resistance.

tocotrienols and HMG CoA reductase

'alpha-tocotrienol (alpha-T3), a vitamin E analogue and HMG CoA reductase (HMGR) inhibitor'

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12656204

As cholesterol is removed through the bile, liver gall bladder and gut function are important - Jan mentioned CCK and sulphate, I think the gall bladder emptying depends on CCK. Also acid entering the duodenum triggers the gall bladder, so ensuring sufficient stomach acid is wise.
The bowel flora are imporant too...

Serum cholesterol and bowel flora in the newborn.

'Lactobacilli organisms predominate in the stools when serum cholesterol is low and may play a role in the metabolism of cholesterol'

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=45573&dopt=Abstract

Good luck,

Ray


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