Posted by JLx on November 10, 2004, at 12:19:04
In reply to Re: Vit E and increased death risk? » JLx, posted by Larry Hoover on November 10, 2004, at 11:41:01
> > > > What might be a good amount to take then? Seems to me I've heard not to take too much, but I forget why and how much "too much" is supposed to be. I generally take between 400 and 800 IU.
> > > >
> > > > JL
> > >
> > > Based on the National Institutes of Health review, the UL is set at 1,000 mg/day (defined as 1,000 IU). However, and this is a large issue, the uncertainty factor for the UL was set at 36. Thus, the lowest observable adverse effects level is 36,000 IU/day, *and* the adverse effects (clotting disturbances) were primarily attributed to deficiency in vitamin K, such that the effect of the vitamin E was not properly balanced.
> > >
> > > I take 1600 per day, and I think I might increase it. I'm nowhere near 36,000, and if anything, my blood is too thick.
> > >
> > > Lar
> >
> > What do you make of this?
> >
> > Vitamin E May Increase Death Risk, Researchers Say http://www.washingtonpost.com/wp-dyn/articles/A39261-2004Nov10.html
> >
> > JL
>
> I want to read the full-text of the paper, before I come to any conclusions of any sort. As mentioned in this article, there was a study that found that beta-carotene supplements had adverse effects, but the whole experimental model used was devoid of real-life applicability. Beta-carotene is never consumed in isolation, and it may well be that other nutrients were poorly supplied that were necessary for everything to work well. Until I see this complete article, I'm not convinced of anything. Vitamin E intake should be balanced by other antioxidants. I have no idea what the underlying study protocols were.
>
> LarSorry, I didn't realize that it was available online: http://www.annals.org/cgi/content/full/0000605-200501040-00110v1
Some reaction: http://www.crnusa.org/PR04_1110CRNAIM.html
JL
poster:JLx
thread:412398
URL: http://www.dr-bob.org/babble/alter/20041108/msgs/414249.html