Posted by raybakes on October 22, 2004, at 18:02:06
In reply to Re: Supplements for brain fog? » raybakes, posted by tealady on October 22, 2004, at 7:34:19
> >My own practitioner gave me something by jarrow called 'homocysteine pf' yesterday which helped me massively. I talked to her about my concerns about my poor methylation and how it's required for creatine prouction and acidity buffering - so we checked it out and found I was really high in folate (like Jan) but couldn't use it - homocysteine PF got my folate working (checked with kinesiology). As glutamine and methylation improve my fog too, I think part of the 'fogginess' may be because I'm too acid.
>
>
> Hi Ray,
> I looked up homocysteine PF by Jarrow yesterday(and had a glance at a few other supps you take too)
> http://www.iherb.com/tmgb12b6tab.html
>
> Vitamin B6 (Pyridoxine HCI) 15 mg 750%
> Methyl B12 (Methylcobalamin)250 mcg 4167%
> Folic Acid 400 mcg 100%
> Trimethylglycine (TMG) 500 mg (Anhydrous Betaine)
>
> so it looks to me like it just has normal Folic acid in it..not the special form you mentioned(FOLINIC ACID (5-formyl tetrahydrofolate))
> ..but it does have Betaine in the TMG form. Lar takes that on I think..the TMG.
> Do you think it's the TMG?
>
> TMG is another I have to order from O'seas.
> Sigh, and I'm beginning to run out of the stuff I bought in England..should have bought a lot and posted it back..as well as imported some from the US into England.
>
> Twas enough getting some citrate forms of Mg, Ca, zinc, and a few others like a higher dose Ferrous fumurate etc..as well as progesterone and oestradiol<g>.
>
> I was taking 500mcg Folic acid together with a multiB for a while..didn't notice any diff..in fact I feel a lot less panicy since dropping the CoQ10 and folic acid (labeled folate..folic acid 500mcg)and more able to cope with some tasks...not big tasks..little things like making a phone call.
>
> On another forum I remember now it was found we need NADPH and oxygen to break down glutiathone...bet I'm short there...everything abouyt me keeps coming up with a shortage of NADPH and oxygen, sigh.
>
> I'll find the link
> http://forums.about.com/ab-thyroid/messages?msg=52183.49
>
> oh yes you migh be interested in this too
> http://forums.about.com/ab-thyroid/messages?msg=52183.47 ..just to change the topic around
> I'm a lot better off with more carbs..and I've found more since..just can't remember what or where now, sigh
> Oh yes on not breaking down chloresterol..another thing I've got..something about the low carb diet preventing chloresterol catabolizing to CoQ10 I think from memory..won't change onto that one!
>
>
> Just to be more complicated..I also have difficulty with all forms of B12..methylcobalamin, hydroxycobalamin injections..my hands turn either bright red or a purply shade and tingly..same with my feet.
> My Mum's hands go a bit red..not as severe as mine. Happens all the time..not as severe if I keep up with the injections but still happens..that's why when I got my B12 levels up I stopped! I even had multiB's made up w/o the B12 for a while just to see if I felt better.
> I sem to be fine witha little cyanocobalamin that is in the multiB's over in Oz at present..well I don't notice much diff anyway.
> This may possiby be a G6PD partial deficiency or perhaps that combined with methaemoglobulin problesm that I seeme to have after a dental anesthetic last year.
> It's on the forum here last Sept.somewhere. If you have anything like that I could look up the posts..doubt it though. on the other had, if you know what it is, I'd love to know for sure!
>
> Found out I don't vasoconstrict...last hole I just skipped the anesthetic..drill felt exactly the same.
> Today I found out I'm lowish on ADH (Vasopressin)..hence the too little vasoconstriction, sigh
> yeah I learnt if one has a needle always get the adrenalaine..then take cortisol after I guess to lower it maybe...
> Gee it makes it err challenging.
>
>
> That's why I'm trying to go to uni to learn enough to figure it out..takes a long time though..especially when I can't just order the tests I need, sigh. Just wish I had a higher fraction of my old brain left to learn and think with.
>
> And all these things seem to cause a tad of anxiety, depression etc, LOL
>
> Jan
Hi Jan, have got to get to bed, so can't answer all your questions today....but yes homocysteine pf only contains folate, but it works wonderfully for me, must be just a good balance for my system.
I was wrong about folinic acid it's tetrahydrofolate, and not fully activated to it's methyl state. But folate to tetrahydrofolate still needs 4 NADPH molecules, and to make the methyl tetrahydrofolate in needs methyl B12, B2 and another NADPH. when folate is used, it then needs B6, manganese in one step, then B2, NADPH and methyl b12 again - if any one of these is in short supply, it all fails! If your low NADPH, that might be why methyl B12 causes a problem, it might accelerate the decline of NADPH?Ray
>
poster:raybakes
thread:359642
URL: http://www.dr-bob.org/babble/alter/20041022/msgs/406103.html