Posted by raybakes on October 17, 2004, at 6:31:25
In reply to creatine/methylation,B12, Folate, sulfation, CoQ10 » raybakes, posted by tealady on October 15, 2004, at 19:19:05
What type of betaine do you take?
Hi Jan, I take betaine by an english company called metabolics - betaine HCl does contain betaine but not enough to make much of a difference to methylation.
> >
> What is folinic acid..folinic acid is methyl tetrahydrofolate! It's the active form of folate - a lot of people have a genetic error that makes it difficult for them to activate folate - they can have plenty of folate, but very low active folate - which form of folate were you tested for?
My folate blood levels before any supps were ABOVE range though...and so were my Mum's.
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might be because high because of the inability to activate it?> Both my Mum's and my blood levels of B12 were low, and both had folate above range..Her B12 was lower than mine and folate higher...almost like our bodies try to replace the low B12 with folate?
I've heard that sometimes one can mask a deficiency in the other too..
> I do notice my Mum has a far better memory after B12 needles (hydroxycobalamin), but she hasn't had any for a while. Before the needles it was difficult to hold conversation with her. So I'm pretty sure B12 can help with Alzheimer's type symptoms at least for some.
Homocysteine has been linked to alzheimers...
> I couldn't get a homocysteine test. (local GP told me "homocysteine doesn't exist in Australia"..his exact words <g>)
wouldn't trust ANYTHING this guy says!!!
>
> On B12 and me...I stopped taking it last February? My blood levels were fairly good then.
> The reason I stopped taking it was I always had strange reactions to B12 needles, and to a lesser extent the methylcobalamin sublinguals. I've got some old posts on here about this I'll try to find as my memory is poor.As my methylation is poor, any supplement that needs to be methylated i do badly with - if it's pre methylated, I'm much better... eg folate, DMG, lysine, choline, and will have to find some methylcobalmine(who's your's made by?)
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> CoQ10..yeah I always knew about the oil based type being the only type to take. Maybe in Oz we are ahead in something!<g>Didn't know, but should have guessed!
> .
> Maybe one only needs to get it to a certain level or maybe I needed more of other nutrients for balance, but I'm not taking it againmight need to look at the electron transport chain in the mitochondria, to see what you need to balance - glutathione comes up again! - also radicals like superoxide.
>
> Interesting. Both dopamine and tyrosine hydroxalase with me appear to need a bit of a hand(I think). I thought it might be the P5P B6 here.p5p is for decarboxylase enzymes - dopa to dopamine, tyrosine to tyramine, 5 hydroxytryptophan to serotonin, glutamate to gaba, and histidine to histamine.
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> Gee I really get lost trying to work out sulphation. I have an article on it I tried to work thruI'm still confused by sulphation too! sometimes it activates, sometimes deactivates, sometimes for transport, and sometimes structural!
> Also on allergy tests and elimination diets and retrials I am sensitive to sulphur preservatives. Maybe sensitive to sulphur based drugs too..at least I get nausea and feel dreadful after a few days, so I avoid them.
Think that's sulphites, they are metabolised to sulphate by 'sulphite oxidase'. Too much sulphite can destroy B1, B6, and folate.
> Because of this I've avoided any sulfate form of supps. Last month I did have a zinc sulfate (one capule..50 mg of zinc sulphate monohydrate) and soon after ended up vomiting, sweating ,shakin for about 30 mins or maybe an hour? Then I was OK. Any thoughts on this?Zinc sulphate might be a bit like taking epsom salts....will draw a lot of water into the gut...I've had a similar reaction too!
Hope that's helped!
Ray
poster:raybakes
thread:402926
URL: http://www.dr-bob.org/babble/alter/20040928/msgs/404070.html