Posted by Larry Hoover on October 12, 2004, at 13:32:43
In reply to Re: What'dya think of leaky gut syndrome?..Ray? » tealady, posted by raybakes on October 12, 2004, at 13:15:08
> > I've never shown any allergies to wheat, gluten or milk on tests either.
>
> Wheat and milk allergies do usually go hand in hand with autoimmune disease - and the more resistant we are to giving them up, is quite often a sign we're allergic to them too! You might be OK but it's certainly worth excluding them for a while..Hey. I'm just going to jump in here with a novel concept. Within the complex milk proteins and wheat proteins are sequences of amino acids which, if liberated during digestion, have opioid and hormonal acivity. There are numerous such sequences in milk proteins, including one of the better studied ones, beta-casomorphine-7. It is derived from the milk proteind casein, and as you can infer from the name, it is an endorphin-like opioid binding protein. It also directly mediates histamine release. So, it perturbs peristalsis, and inflames tissues, in the complete absence of classical allergic response mediated by immunoglobulins.
The generic term for this class of substances is exorphin. I just thought I'd put a bug in Ray's brain. ;-)
I found a paper a few years ago that described industrial milk processing techniques specifically engineered to ensure maximization of yield of exorphin sequences prior to the creation of processed cheese. I've heard people say that they crave certain "plastic" cheeses, and there may be some truth to that, via opiate-mediated addiction.
Wheat has similar sequences. Wheat and milk intolerance can be due to processes entirely distinct from allergy. Individual sensitivity to these substances varies substantially, and can change over time. Once sensitized, it is possible that such sensitization is permanent. Ray, this might explain your rechallenge experience, with substantially exacerbated symptoms on re-exposure.
Lar
poster:Larry Hoover
thread:401487
URL: http://www.dr-bob.org/babble/alter/20040928/msgs/402182.html