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Re: what I'm taking » Larry Hoover

Posted by Simus on August 17, 2004, at 22:17:48

In reply to Re: what I'm taking » Simus, posted by Larry Hoover on August 14, 2004, at 12:15:08

> One simple test of adrenal stress is to try some licorice. Do not use DGL, though. That is De-Glycyrrhizinated Licorice. Glycyrrhizin is the compound that blocks the enzyme that activates cortisol. I'll snip from an unreferenced source...."Glycyrrhetinic acid, a metabolite of glycyrrhizin, inhibits the renal conversion of cortisol to cortisone by inhibiting the enzyme 11 beta-hydroxysteroiddehydrogenase in the kidney." Cortisol is "potential cortisone", in the sense that circulating cortisol levels tell the hypothalamus that the adrenal glands are functioning up to par. By inhibiting conversion to cortisone, you not only reduce stress response, you also trick the hypothalamus into giving the adrenals a little holiday, by inhibiting the CRH cascade. Don't take licorice for more than four weeks. It can lead to other disturbances.

Larry,

If I took licorice, what would I be looking for as proof that I do indeed have adrenal stress? Just more energy or feeling better overall? Or is there something more specific?

Thanks,

Simus


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