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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by iforgotmypassword on July 7, 2006, at 2:01:17
just wondering what may cause apathy, amotivation, and hardened cognitive processes with heavy pot use back in the teens. i mean neurochemically speaking, to try and deduce what meds may be effective to resolve such issues, but also better understand the neurochemical and neuroanatomical cause. have any SPECT scans been done?
pot use probably isnt what started things with me. it is most likely not that at all. but i think it took my problems and made things a lot worse (albeit it having initially made things better.) my reaction to pot was ballistic and very different from what other people experience, and very difficult to handle for other people, and then i'd be ruined for days. i was not mellow. but the end result, well, i am basically emotionally dead, but automatic around people. i probably would still be like this today but pot really didn't help.
does anyone have any clues on the post-pot effects on the brain, and what clues for therapeutic intervention there may be, even for people with similar symptoms and experience even without the having ever used pot maybe.
Posted by mike lynch on July 7, 2006, at 2:01:18
In reply to neurochemistry of post-pot apathy; RESOLVING MEDS, posted by iforgotmypassword on July 6, 2006, at 23:24:15
There is no evidence of long lasting cognitive effects, brain abnormalities with marijuana use..
I refer you to this studyhttp://toxsci.oxfordjournals.org/cgi/content/abstract/17/2/321
For a simple conclusion of that article
64 rhesus monkeys tested, half of which were exposed to daily or weekly doses of marijuana smoke for a year. The other, by Gordon T. Pryor and Charles Rebert at SRI International in Menlo Park, California, which is still unpublished, looked at over 30 rhesus monkeys that had inhaled
marijuana one to three times a day over periods of 6 to 12 months. Neither study found evidence of structural or neurochemical changes in the brains of the monkeys when examined a few months after cessation of smoking.I think adderall, or a stimulant like that could help reverse apathy.
Posted by bipolarspectrum on July 7, 2006, at 2:01:18
In reply to neurochemistry of post-pot apathy; RESOLVING MEDS, posted by iforgotmypassword on July 6, 2006, at 23:24:15
Hey,
I just wanted to say that many super successful and intellectual people have smoked significant amounts of marijuana in their life... consider the 60;s generation, who consumed enormous amounts of illict drugs, and then preceded to run america... i dont think u need to worry at all.. ive spoked to a neurologist about this who says that all marijuana does is impair short-term memory....
bps
Posted by iforgotmypassword on July 7, 2006, at 2:01:18
In reply to Re: neurochemistry of post-pot apathy; RESOLVING MEDS, posted by bipolarspectrum on July 7, 2006, at 0:45:56
> Hey,
> I just wanted to say that many super successful and intellectual people have smoked significant amounts of marijuana in their life... consider the 60;s generation, who consumed enormous amounts of illict drugs, and then preceded to run america... i dont think u need to worry at all.. ive spoked to a neurologist about this who says that all marijuana does is impair short-term memory....
> bpsbut many people cannot handle pot. they just can't, and the examples of people that can and do wonderfully really takes away from the people that can't. maybe there is an underlying neurological condition that makes one succeptible, or the more libertarian-friendly explaination, maybe psychological predispostion (i.e. their fault, and "not my problem"). i think we need to realize that some people cannot do well with pot.
its just like alcohol. i am not advocating the prohibition of recreational drugs. i wish there was special attention beyond studies using our current methods that can deny that there are problems relating to anything. as with in my case, what has ruined my life, but i don't know what it is, and has no diagnosis, just shoulder-shrugs from supposed professionals.
Posted by bipolarspectrum on July 7, 2006, at 2:01:18
In reply to i think this is the problem, posted by iforgotmypassword on July 7, 2006, at 0:55:52
> but many people cannot handle pot. they just can't, and the examples of people that can and do wonderfully really takes away from the people that can't. maybe there is an underlying neurological condition that makes one succeptible, or the more libertarian-friendly explaination, maybe psychological predispostion (i.e. their fault, and "not my problem"). i think we need to realize that some people cannot do well with pot.Mabye you are correct here... mabye its neurological, genetic, who knows... but if this was the case, i think there would be a larger portion of the population with this problem... its highly unlikely that, if this is a problem, that ur the only one who suffers from it... this is the basis for my arguement that i dont beleive marijuana use has caused u severe damage...
Also, remember, marijuana has most likely had alogner history of usage by people than, for example, alcohol.... im not sure what that means here, but people always claims its 'natural'..
> its just like alcohol. i am not advocating the prohibition of recreational drugs. i wish there was special attention beyond studies using our current methods that can deny that there are problems relating to anything. as with in my case, what has ruined my life, but i don't know what it is, and has no diagnosis, just shoulder-shrugs from supposed professionals.What are ur symptoms specifically?? Cognitive fog?? i should probably reread ur first post but can u reiterate ur mental problems?? i bet with the help of the uber minds on this board that we can bring some peace to ur worries...
bps
Posted by linkadge on July 8, 2006, at 3:51:36
In reply to Re: i think this is the problem, posted by bipolarspectrum on July 7, 2006, at 1:14:54
You are right, some people don't respond too well to marajuanna. Some studies have linked certain gene expression to adverse reactions to marajuanna. I think the study I read said that the users with low activity of COMT seemed to suffer from more advere reactions to marajuanna use.
Different studies say different things. It is all obscured by the fact that if the governement wants a study to support the legality of the substance, then it can find scientists to say whatever they want.
Not saying that you did not have adverse reactions to it. It may have triggered something, but its hard to say exactly what.
Are you sure you were smoking pure weed? Could certain of it have been laced with something else ?
Linkadge
Posted by laima on July 20, 2006, at 15:29:39
In reply to Re: i think this is the problem, posted by linkadge on July 8, 2006, at 3:51:36
Pure weed? Hard to say sometimes, do you think? I used to smoke a long while ago, and I can surely tell you that what I got on the west coast was consistently entirely different from what I got in a large midwestern city. I heard that inland it is often not quite so fresh and so "enhanced" with savory substances like formeldehyde. This info I got from a former coworker who used to sell as a gangmember.> You are right, some people don't respond too well to marajuanna. Some studies have linked certain gene expression to adverse reactions to marajuanna. I think the study I read said that the users with low activity of COMT seemed to suffer from more advere reactions to marajuanna use.
>
> Different studies say different things. It is all obscured by the fact that if the governement wants a study to support the legality of the substance, then it can find scientists to say whatever they want.
>
> Not saying that you did not have adverse reactions to it. It may have triggered something, but its hard to say exactly what.
>
> Are you sure you were smoking pure weed? Could certain of it have been laced with something else ?
>
>
> Linkadge
>
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This is the end of the thread.
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