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Dr. Bob is Robert Hsiung, MD,
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Posted by River1924 on March 23, 2008, at 15:54:42
I saw an article which said remeron might help with akathisia. Any experiences with that? Thanks for any answers. (I doubt if I could use it since I weigh too much anyway.) Roger.
Posted by britney27 on March 23, 2008, at 22:58:03
In reply to akathisia + remeron, posted by River1924 on March 23, 2008, at 15:54:42
Hi River, I found this from Wikipedia
Treatment includes the discontinuation or reduction of dose of the causative agent.
The most common treatment for antipsychotic akathisia is the anticholinergic medication benztropine (Cogentin). But since benztropine is for extrapyramidal side effects such as muscle spasms, muscle stiffness and tremors it is not effective in treating akathisia which is not a true extrapyramidal side effect. Other anticholinergic medications such as diphenhydramine may also be used in the treatment of akathisia.
Akathisia can be reduced by administering other drugs, though effectiveness can vary with more severe cases resistant to most drug treatment. Benzodiazepines like clonazepam (Klonopin) are effective. Some consider the drug of choice for the treatment of akathisia to be beta-blockers such as propranolol (Inderal) or metoprolol. The antihistamine cyproheptadine is also effective, though with shorter effect than beta blockers.
One study showed that vitamin B6 is effective for the treatment of neuroleptic-induced akathisia.
I hope your akathisia improves.
best wishes
Britney
Posted by bleauberry on March 24, 2008, at 20:28:31
In reply to akathisia + remeron, posted by River1924 on March 23, 2008, at 15:54:42
Yeah, I saw the abstract at pubmed about remeron for akathisia. Years ago I had what I think was akathisia. I found that 7.5mg or less of remeron did indeed help, but any more than that made it even worse. It felt to me like the antihistamine and serotonin effects at the super low dose, void of norepinephrine effects, was ok. But I could tell just by the feel of it and by the increased volume of my tinnitus that 7.5mg was the threshold where norepinephrine started to kick in. The norepinephrine component is what made my akathisia worse.
All things considered, I personally believe the smartest option for akathisia is to remove the offending drug and do something else. Akathisia is a sign that something in there is terribly wrong.
This is the end of the thread.
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