Psycho-Babble Alternative Thread 1019135

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Carnosine for unipolar and bipolar

Posted by Hugh on June 2, 2012, at 21:45:22

This study found that carnosine reduces glutamate excitotoxicity. Ketamine also reduces glutamate excitotoxicity.

http://www.ncbi.nlm.nih.gov/pubmed/20043985

This clinical trial, which doesn't look like it's been published yet, used carnosine to treat bipolar disorder.

http://clinicaltrials.gov/ct2/show/NCT00177463

 

Re: Carnosine for unipolar and bipolar » Hugh

Posted by SLS on June 9, 2012, at 6:57:00

In reply to Carnosine for unipolar and bipolar, posted by Hugh on June 2, 2012, at 21:45:22

Thanks, Hugh.


- Scott


> This study found that carnosine reduces glutamate excitotoxicity. Ketamine also reduces glutamate excitotoxicity.
>
> http://www.ncbi.nlm.nih.gov/pubmed/20043985
>
> This clinical trial, which doesn't look like it's been published yet, used carnosine to treat bipolar disorder.
>
> http://clinicaltrials.gov/ct2/show/NCT00177463

 

Re: Carnosine for unipolar and bipolar

Posted by bleauberry on June 30, 2012, at 9:33:46

In reply to Carnosine for unipolar and bipolar, posted by Hugh on June 2, 2012, at 21:45:22

But first we need to know if there is glutamate toxicity. There is a blood spot test that can do that, and show the status of the other amino acids at the same time. That test helps take the guesswork out of it and paints a much clearer picture of what's going on.

 

Re: Carnosine for unipolar and bipolar » bleauberry

Posted by SLS on July 1, 2012, at 1:35:28

In reply to Re: Carnosine for unipolar and bipolar, posted by bleauberry on June 30, 2012, at 9:33:46

> But first we need to know if there is glutamate toxicity. There is a blood spot test that can do that, and show the status of the other amino acids at the same time. That test helps take the guesswork out of it and paints a much clearer picture of what's going on.

Are these tests reflective of what is happening on the other side of the blood-brain-barrier?


- Scott


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